Chronic Wasting Disease: A working hypothesis, the Agent and its Transmission A Logical Causative Agent PART Ib: The Quest for an Agent
نویسنده
چکیده
(Part Ib) Transmissible Spongiform Encephalopathies, and in particular, Chronic Wasting Disease are devastating neuropathologic diseases caused by a unique, but unknown infective agent with high degree of refractivity to ordinary disinfectant and sterilization procedures. Amazingly, a fully described comparison of 28 TSE causal agent characteristics match remarkably well with 28 documented characteristics of Spiroplasma bacteria and/or their lesser cousins, the mycoplasma bacteria. A close resemblance is present for physical structure, such as size and density; agent refractivity to both disinfectants and heat; the unusual characteristics of surface adherence and ground survivability; reaction to hyperbaric oxygen; resistance to bactericidal antibiotics, yet susceptibility to bacteriastatic antibiotics; a comparable response to attenuated agent vaccines characteristics; and lastly comparable infectivity conditions found in blood and lymph. Importantly, B-cells have been implicated in both TSE infectivity and in the mycoplasmal disease process. Blood born bacterial characteristics match extraordinarily well with specifically determined “prion” characteristics. Stunning electron micrographs of helical, CJD-brain inclusions and incontrovertible PCR-DNA results virtually dictate that Spiroplasma and TSE disease are intimately linked. Conclusively, the failure of the scientific community to diligently pursue Mycoplasma and Spiroplasma and their likely role of disease pathogenesis, particularly for TSEs, is a failure in our investigative system of scientific curiosity and prudence.
منابع مشابه
Chronic Wasting Disease: A Review and working hypothesis, the Agent and its Transmission PART I: A Logical Causative Agent
(Part I) Transmissible Spongiform Encephalopathies (TSE) and in particular, Chronic Wasting Disease are devastating neuropathologic diseases caused by a unique, but unknown infective agent with high degree of refractivity to ordinary disinfectant and sterilization procedures. Three criteria are used to identify TSEs 1) neuronal vacoulation, 2) Scrapie Associated Fibrils, and 3) proteins resista...
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(Part IIc) Transmissible Spongiform Encephalopathies (TSE) and in particular, Chronic Wasting Disease (CWD) are devastating neuropathologic diseases caused by a unique, but unknown infective agent with high degree of disinfectant refractivity. Collective literature review and animal observational data has defined two prospective varieties or stains of the infective CWD agent, both suspected to ...
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